Clinicopathologic, phenotypic, and genotypic characteristics of gastrointestinal mesenchymal tumors Jean—franÇois Emile, Nathalie Théou, Séverine Tabone, Annie Cortez, Philippe Terrier, Marie—thérèse Chaumette, Catherine Julié, Philippe Bertheau, Anne Lavergne—slove, Jean Donadieu, Alain Barrier, Axel Le Cesne, Brigitte Debuire, Antoinette Lemoine Clinical Gastroenterology and Hepatology Volume 2, Issue 7, Pages 597-605 (July 2004) DOI: 10.1016/S1542-3565(04)00243-5
Figure 1 Frequency of deleted codons of exon 11. (A) Frequency of deleted codons in all GISTs. (B) Frequency of deleted codons in all malignant and nonmetastatic GISTs. Clinical Gastroenterology and Hepatology 2004 2, 597-605DOI: (10.1016/S1542-3565(04)00243-5)
Figure 2 Detection of KIT mutants by length analysis of PCR products (LAPP). Exon 11 (blue peaks): samples without mutated alleles (A, D) had only 1 peak at 270 base pairs (WT), whereas samples with 1 (B) or 2 (C) mutant alleles had 1 (B) or 2 (C) additional peaks. Exon 9 (green peaks): samples without mutated alleles (A, B, C) had only 1 peak at 196 base pairs (WT), whereas samples with 1 mutant allele had an additional peak (D). The size of the mutant PCR product (M) corresponded to the number of deleted base pairs. The small red peaks correspond to the size markers. Clinical Gastroenterology and Hepatology 2004 2, 597-605DOI: (10.1016/S1542-3565(04)00243-5)