Efficacy of Sofosbuvir and Daclatasvir in Patients With Fibrosing Cholestatic Hepatitis C After Liver Transplantation  Vincent Leroy, Jérôme Dumortier,

Présentation au sujet: "Efficacy of Sofosbuvir and Daclatasvir in Patients With Fibrosing Cholestatic Hepatitis C After Liver Transplantation  Vincent Leroy, Jérôme Dumortier,"— Transcription de la présentation:

1 Efficacy of Sofosbuvir and Daclatasvir in Patients With Fibrosing Cholestatic Hepatitis C After Liver Transplantation  Vincent Leroy, Jérôme Dumortier, Audrey Coilly, Mylène Sebagh, Claire Fougerou-Leurent, Sylvie Radenne, Danielle Botta, François Durand, Christine Silvain, Pascal Lebray, Pauline Houssel-Debry, Nassim Kamar, Louis D’Alteroche, Ventzislava Petrov-Sanchez, Alpha Diallo, Georges-Philippe Pageaux, Jean-Charles Duclos-Vallee Georges-Philippe Pageaux, Jean-Charles Duclos-Vallée, Audrey Coilly, Eric Bellissant, Danielle Botta-Fridlund, Alpha Diallo, Jérôme Dumortier, François Durand, Christophe Duvoux, Claire Fougerou-Leurent, Vincent Leroy, Ventzislava Petrov-Sanchez, Alain Renault, Alexandra Rohel, Anne-Marie Roque, Anne-Marie Taburet, Aurélie Veislinger Vincent Leroy, Jérôme Dumortier, Audrey Coilly, Mylène Sebagh, Claire Fougerou-Leurent, Sylvie Radenne, Danielle Botta, François Durand, Christine Silvain, Pascal Lebray, Pauline Houssel-Debry, Nassim Kamar, Louis D’Alteroche, Ventzislava Petrov-Sanchez, Alpha Diallo, Georges-Philippe Pageaux, Jean-Charles Duclos-Vallee Georges-Philippe Pageaux, Jean-Charles Duclos-Vallée, Audrey Coilly, Eric Bellissant, Danielle Botta-Fridlund, Alpha Diallo, Jérôme Dumortier, François Durand, Christophe Duvoux, Claire Fougerou-Leurent, Vincent Leroy, Ventzislava Petrov-Sanchez, Alain Renault, Alexandra Rohel, Anne-Marie Roque, Anne-Marie Taburet, Aurélie Veislinger  Clinical Gastroenterology and Hepatology  Volume 13, Issue 11, Pages e2 (November 2015) DOI: /j.cgh Copyright © 2015 AGA Institute Terms and Conditions

2 Figure 1 Cumulative incidence of complete clinical response over time according to treatment regimen. No statistical difference was observed between the 2 arms. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

3 Figure 2 Evolution of AST, ALT, alkaline phosphatase (ALP), and γGT serum levels over time. Results are presented as median (circle) and IQR (bars). Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

4 Supplementary Figure 1 Evolution of total bilirubin serum levels over time. Results are presented as medians (circle) and IQR (bars). Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

5 Supplementary Figure 2 Early viral decay according to treatment regimen. No statistical difference was observed between the 2 arms. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions